Modafinil For Narcolepsy Dosage Benefits and Considerations
Modafinil is a safe, well-tolerated stimulant drug that has low potential for abuse or dependence. It is used to treat excessive daytime sleepiness related to narcolepsy, shift work disorder, and obstructive sleep apnea.
It comes as an oral tablet and is typically taken in the morning for narcolepsy, sleep apnea, or shift work disorder. But the best time to take it depends on what you're treating.
Dosage
Modafinil 200 Australia, also known as Provigil, is a wake-promoting drug that has been shown to be effective in treating some symptoms of narcolepsy. It is a safe, well-tolerated drug with a low risk of side effects. It is not a cure for narcolepsy and should be used in conjunction with other treatments, such as sleep therapy.
In two nine-week, double-blind, placebo-controlled studies of narcoleptic patients, 200 or 400 mg of modafinil per day significantly improved EDS on several standard measurements (Epworth Sleepiness Scale, ESS; Health Related Quality of Life Questionnaire, EQ VAS; and EQ5D). The improvement was more pronounced in the narcolepsy patients than in the OSA patients.
The drug can impair your thinking or reaction time and you should be careful if driving or operating machinery. You should let the DVLA know that you are taking this medication, and you will need regular reviews of your condition by your consultant to check whether the dose needs to be adjusted.
Side Effects
Modafinil is a first-choice medication to treat daytime sleepiness associated with narcolepsy and shift work sleep disorder. It's also used to help people with insomnia avoid trouble sleeping at night (insomnia).
Unlike other wake-promoting drugs, modafinil doesn't cause sleepiness when you take it later in the day. However, it may make you feel tired if you try to go back to sleep after taking it.
In some people, modafinil can cause chest pain or changes on an electrocardiogram (ECG). It's important to tell your doctor if you have any heart problems or other serious health problems.
The exact amount of modafinil (Modawake 200) you need to take depends on your age and the condition being treated. You should always follow your doctor's instructions exactly. The time of day you take the medication also matters. For narcolepsy and sleep apnea, you should usually take it in the morning. For shift work sleep disorders, you should take it about an hour before your work shift starts.
Precautions
Modafinil is a wakefulness-promoting drug used to treat narcolepsy. It is effective at alleviating sleepiness and is well tolerated by patients with narcolepsy with or without cataplexy, in comparison to other CNS stimulants such as methylphenidate (Provigil) or d-amphetamine. It does not cause rebound hypersomnolence or other adverse effects seen with other stimulants such as amphetamines.
Modafinil may harm an unborn baby. Women of childbearing potential should use reliable methods of birth control while taking it and for one month after stopping it. Modafinil can make some forms of birth control less effective. Talk to your doctor about what birth control is best for you.
Your dose and schedule of taking this medicine should be carefully monitored by your doctor. Follow your doctor's instructions exactly. You should not take more or less of it or do it more often than prescribed by your doctor. Doing so can cause serious side effects. Your doctor will do blood tests before starting this medicine and while you are taking it to check your liver function.
Interactions
Using this medication with some other medicines may cause an increased risk of side effects. In many cases, your doctor may recommend that you avoid taking both medicines together. Your doctor may also change your doses or how often you use either medicine.
Modafinil is a wake-promoting drug that is prescribed for narcolepsy and also taken without prescription by healthy people to improve decision-making, problem-solving and enhance alertness. Scientists from Harvard and Oxford universities have analyzed all the research on the subject and concluded that modafinil is safe and does not make you stupid, but it can improve working memory and flexibility of thought.
The mechanism by which modafinil reduces excessive daytime sleepiness is not fully understood, but it is believed to increase the activity of certain brain chemicals. In clinical studies, modafinil improved standard measurements of narcolepsy such as the Epworth Sleepiness Scale (ESS) and the Health-Related Quality of Life instrument (EQ-5D).